Kirk Hammond, the corresponding author on the study, explained that a single administration of an agent that both reduces blood sugar and increases heart function would be attractive to patients with diabetes. The study appeared in the March 11, 2019, issue of Human Gene Therapy.ĭr. The study could lead to new clinical treatments for diabetes-related left ventricle dysfunction, they say. Working with mice, the researchers showed that a single injection to promote the expression of the hormone urocortin 2 (UCn2) increased left ventricle function and improved how the body processed glucose.
Researchers with the VA San Diego Healthcare System and the University of California San Diego have shown that a gene transfer technique can combat heart dysfunction caused by diabetes. The team has shown, in mice, that gene therapy can improve a diabetes-related heart ailment. Kirk Hammond's lab at the VA San Diego Healthcare System and the University of California San Diego. Image: Dimosthenis Giamouridis is a research associate in Dr.
